Dr Rajesh Kumar Jha's research group from CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, is working on the biology and management of gynaecological endocrine and metabolic disorders such as endometriosis and Polycystic Ovarian Syndrome (PCOS). These disorders are routinely observed in nearly 10% of infertile women visiting gynaecological clinics and affect women’s day-to-day life along with pregnancy/conception. Thus, his group is studying the disturbed endocrine/hormone-associated molecular signalling in the ovary and uterus for disorders management and successful pregnancy.

For his outstanding work in this field, he has received the prestigious ICMR-DHR International fellowship for Young Biomedical Scientists 2022-23 to explore the gene-specific function of the ovary and endometrium using advanced Genome editing (also called gene editing) transgenic approach such as CRISPR-Cas9 system at Baylor College of Medicine, Houston, Texas, USA.

At Baylor College of Medicine, he will study the endometrial tissue-specific modified gene response on the ovarian and endocrine molecular signalling for ovulation and pregnancy using the CRISPR-Cas9 system, which will help in the ovarian and uterine disorders effective management.